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Studies on chemical constituents of Callicarpa pedunculata / 中草药
Zhongcaoyao ; Zhongcaoyao;(24)1994.
Article in Zh | WPRIM | ID: wpr-570200
Responsible library: WPRO
ABSTRACT
Object To study the chemical constituents of whole plant of Callicarpa pedunculata R Brown Methods Various chromatographic techniques were employed for isolation and purification of its constituents; and their structures were identified by spectral analysis (IR, MS, 1HNMR, 13 CNMR) and chemical evidences Results Ten compounds were obtained from the chloroform extract of the whole plant Among them four were diterpenoids which were identified as: 14 ?-hydroxy-7, 15-isopimaradien-18-oic acid (Ⅰ), 16 ?, 17-dihydroxy-3-oxo-phyllocladanetriol (Ⅱ), 8, 11, 13, 15-abietetraen-18-oic acid (Ⅲ), and 6 ?-hydroxy nidorellol (Ⅳ); 2 flavonoids: 5-hydroxy-3, 4′, 7-trimethoxy-flavone (Ⅴ), and 3, 5-dimethyl kaempherol (Ⅵ); and the others were ursolic acid (Ⅶ), myoinositol (Ⅷ), ?-sitosterol (Ⅸ), and ?-amyrin (Ⅹ) Conclusion Compounds Ⅰ, Ⅱ, Ⅲ, Ⅳ were found in this plant for the first time and it was of interest to note that they were of different diterpenoid skeletons The content of ursolic acid attained to a high level up to 1%, which may be exploited as a natural resource for medical purposes
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Full text: 1 Index: WPRIM Language: Zh Journal: Zhongcaoyao Year: 1994 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Zhongcaoyao Year: 1994 Type: Article