Mechanism of Borneolum Combined with Rhizoma Chuanxiong in Counteracting Cerebral Ischemia with Reperfusion Injury / 广州中医药大学学报

ABSTRACT

Objective To explore the mechanism of Borneolum combined with Rhizoma Chuanxiong in counteracting cerebral ischemia with reperfusion injury.Methods Rat Model of cerebral ischemia with reperfusion injury was set up by occlusion of bilateral carotid arteries.The effect of Borneolum combined with Rhizoma Chuanxiong on the content of nitric oxide(NO)and free radicals of model rat brain tissue was observed.Results Borneolum combined with Rhizoma Chuanxiong decreased the lipid peroxide(LPO)content and increased the activity of superoxidase(SOD)in model rat brain tissue(P