A Clinical Observation on Preventive Effect of Spleen-Strengthening and Kidney-Reinforcing Method on Leukopenia Caused by Chemotherapy / 广州中医药大学学报

ABSTRACT

Objective To observe the effect of spleen-strengthening and kidney-reinforcing method on leukopenia in patients with malignant tumor after chemotherapy.Methods Seventy-one patients with malignant tumor were randomly allocated to Group A(n=37) and Group B (n=34).Group A was treated with spleen-strengthening and kidney-reinforcing herbal medicine and chemotherapy and Group B with chemotherapy only. The treatment course lasted 28 days.Blood routine examination was carried out before chemotherapy and on 7 th,9 th,12 th,15 th,18 th and 21 st day of chemotherapy.Results In Group A,5 cases of leukopenia were found, 3 in degree Ⅰ, 1 in degree Ⅱ and 1 in degree Ⅲ,the incidence being 13.5%; In Group B,25 cases of leukopenia were found, 3 in degree Ⅰ,13 in degree Ⅱ,8 in degree Ⅲ and 1 in degree Ⅳ, the incidence being 73.5%. There was significant difference between the two groups (P