Literature Analysis of 73 Cases of Adverse Reactions of Xiangdan Injection / 中国中医药信息杂志

ABSTRACT

Objective To discuss the features and general patterns of adverse drug reaction (ADR) of Xiangdan injection, and provide reference for clinical safe medication. Methods The author retrieved 73 cases about ADR of Xiangdan injection in domestic medicine journals from 2002 to 2012, collected and analyzed the information about patients’ general conditions, medicine dosage and solvent, ADR happening time, clinical manifestations, and prognosis. Results The main clinical manifestation of ADR was anaphylactic shock, with the incidence rate of 46.58%(34/73), and the happening time was mainly within 30 minutes after the patients received Xiangdan injection (46/73, 63.01%). Conclusion TCM injection should be used properly. At the same time, clinical medication monitoring should be strengthened, with a purpose to reduce and avoid ADR of Xiangdan injection.