Angiotensin Ⅱ stimulates the synthesis of nucleic acid, protein and collagen in cultured hepatic stellate cells in rats / 中华消化杂志
Chinese Journal of Digestion
;
(12)1996.
Article
in Chinese
| WPRIM
| ID: wpr-570474
ABSTRACT
Objective To investigate the effects of different doses of angiotensin Ⅱ(Ang Ⅱ) on hepa tic stellate cells(HSC) proliferation and collagen synthesis in rats. Methods The pronase E and collagen Ⅰ were used to isolate HSC, 3H TdR, 3H Leu and 3H Pro incorporation methods were used to evaluate the effects of different doses of AngⅡ on HSC DNA, protein and proline synthesis. Results It showed that 10 -9 ~10 -6 mol/L AngⅡ could significantly increase the 3H TdR incorporation rate of HSC ( P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Digestion
Year:
1996
Type:
Article
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