The effects of ventilation with high density oxygen on the strength of gastrointestinal anastomosis
Annals of Surgical Treatment and Research
;
: 17-22, 2015.
Article
in English
| WPRIM
| ID: wpr-57053
ABSTRACT
PURPOSE:
The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses.METHODS:
Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats and assigned to an oxygen/nitrous oxide mixture with a fraction of inspired oxygen of 30% in groups 1 and 3 and 80% in groups 2 and 4. The measurements of perianastomotic tissue oxygen pressure, bursting pressure, level of hydroxyproline were evaluated and compared in all groups.RESULTS:
The perianastomotic tissue oxygen pressures, bursting pressures and levels of hydroxyproline were identified as significantly high in groups 2 and 4, administered a fraction of inspired oxygen of 80%, compared to groups 1 and 3, administered a fraction of inspired oxygen of 30%.CONCLUSION:
Perioperative supplemental oxygen contributes positively to the anastomotic healing.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Ventilation
/
Rats, Wistar
/
Hydroxyproline
Type of study:
Controlled clinical trial
Limits:
Animals
/
Humans
/
Male
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2015
Type:
Article
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