Assay of Danshensu and Protocatechuic Aldehyde in Compound Danshen Dropping Pill by HPLC / 中药新药与临床药理
Traditional Chinese Drug Research & Clinical Pharmacology
;
(6)1993.
Article
in Chinese
| WPRIM
| ID: wpr-570610
ABSTRACT
Objective:
To separate and determine two constituents of Danshensu and protocatechuic aldehyde in compound Danshen Dropping Pill.Methods:
The chromatographic conditions were as follow Nucleosil C18 column, a mixture of methanol-water-acetic acid glacial (19∶80∶1) as the mobile phase with a flow rate of 1 mL per minute and the detection wavelength at 279 nm. P-hydroxybenoic acid was used as internal standard.Results:
The calibration curves were linear in the range of 10~80 mg/L (r=0.9995) for Danshensu and 2~16 mg/L (r=0.9996) for protocatechuic aldehyde . The average recovery of Danshensu and protocatechuic aldehyde were 99.4 %and 99.5 %respectively.Conclusion:
This method is accurate, simple and convenient, rapid and reproducible and can be used for the quality control of compound Danshen Pill.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Traditional Chinese Drug Research & Clinical Pharmacology
Year:
1993
Type:
Article
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