Orlistal combined with low calorie diet in the treatment of obesity with non-alcoholic steatohepatitis / 中华消化杂志

ABSTRACT

Objective To evaluate the efficacy and safety of orlistat combined with low calorie diet in the treatment of obesity with non-alcoholic fatty liver disease. Methods Orlistat 120 mg, three times a day, combined with low calorie diet for a cause of 24 weeks, were given to the 60 non-alcoholic fatty liver disease (NAFLD) patients whose body mass index (BMI) were between 27 and 40. Results ①The percentage of mean weight loss and mean decreased BMI were both (10.76? 4.52 )% of their initinal weight at 24 weeks treatment. ②ALT, AST, GGT and total bilirubin was significantly decreased ( P