Inhibitory effect of urinary trypsin inhibitor on protease activity in the colonic tissues of ulcerative colitis rats / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)1987.
Article
in Chinese
| WPRIM
| ID: wpr-571875
ABSTRACT
Objective:
To determine the effect of urinary trypsin inhibitor(UTI)on protease activity in the colonic tissues of ulcerative colitis(UC) rats.Methods:
The experimental UC was induced in Wistar rats by enema with 0.25ml of 18% 2,4-dinitrobenzenesulfonic acid (DNBS) dissolved in ethanol.UTI was injected into the rats through the caudal vein.Protease activity present in colonic tissues was determined on gelatin zymograms.Results:
The protease activity which presented in colonic tissues of the group treated with UTI was only 1/3 that of the control.Conclusion:
The protease activity decreased significantly after we treated the rats with UTI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chongqing Medical University
Year:
1987
Type:
Article
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