Effects of microRNA and PI3K/AKT signaling pathway on cardiac development / 国际儿科学杂志

ABSTRACT

MiRNA can regulate cell proliferation and differentiation,and promote the development of organisms.Phosphoinositide 3-kinase/protein kinase B(PI3K/AKT) signaling pathway plays an important role in cell proliferation and differentiation,and also in organ and organization development.Studies concerning miRNA and PI3K/AKT signaling pathways in cardiac development and their relationship might help explain the pathogenesis of cardiac malformations and related diseases.