The effects of recognition of emotional words on ERPs of patients with major depression / 中华物理医学与康复杂志

ABSTRACT

Objective To investigate the effects of recognition of emotional content words on event-related potentials (ERPs) of patients with major depression. Methods ERPs were recorded in 16 patients with major depression and 18 healthy subjects while they performed a visual Chinese emotional content words recognition task. The study used a word identification task consisting of 20% negative and 20% positive words as well as 60% neutral words. Results The ERPs demonstrated similar waveform (N90,P160,N250,P290,N350,P490,N650) between depression patients and normal group, but its components were different. Amplitudes of many ERPs components in patients group were significantly decreased but N250 were significantly increased in FZ and F4 as compared with those of the normal groups (P