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THE EXPRESSION OF AGRIN IN RAT CORTEX DURING THE POSTNATAL TIME / 解剖学报
Acta Anatomica Sinica ; (6)1955.
Article in Chinese | WPRIM | ID: wpr-572216
ABSTRACT
Objective To observe the expression of heparan sulfate proteoglycan(HSPG)-Agrin in rat cortex of postnatal time in order to understand the relation between the development of cortex and agrin. Methods We performed immunohistochemical analysis of agrin expression in the postnatal rat cortex with agrin-specific polyclonal antibody. Results Agrin expression was shown to have significant differences in the different periods of postnatal time.It increased from postnatal 2 day(p2) to postnatal day 6(p6),then declined steadily after p6 and reached adult levels by 4w.In this periold of time,agrin has different expression peak following to the cortex layer development.

Conclusion:

Agrin is related to the development of cortex and may play an important role in the developing of central nervous system.;

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Acta Anatomica Sinica Year: 1955 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Acta Anatomica Sinica Year: 1955 Type: Article