The value of apparent diffusion coefficient measurement of diffusion weignted imaging in diagnosis of brain abscess / 重庆医科大学学报

ABSTRACT

Objective:To explore the value of apparent diffusion coefficient (ADC) measurement of diffusion weighted imaging(DWI) in diagnosis of brain abscess.Methods:Ten patients with brain abscess (8 being histologically verified,2 clinically confirmed) were examined using conventional MRI and DWI before operations or medications.ADC values of pus,abscess walls, edema at the periphery of abscess and opposite normal white matters of all 10 cases were measured with b values (0 s/mm~2 and 1000 s/mm~2) and their ADC mean values were calculated.Results:The ADC mean values in 10 cases of pus cavity,abscess walls,edema at the periphery of abscess and opposite normal white matters were (0.57?0.11)?10~(-3)mm~2/s,(1.14?0.06)?10~(-3)mm~2/s,(1.74?0.21)?10~(-3)mm~2/s and (0.77?0.05)?10~(-3)mm~2/s,respectively.The differences in the ADC mean values were significant between either two parts of pus cavity,abscess walls,edema at the pariphery of abscess and opposite normal white matters(P