Intraocular penetration of levofloxacin in rabbit eyes following topical and subconjunctival administration / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-572727
ABSTRACT
Objective:
To compare the ocular tissue concentrations and pharmacokinetic parameters in rabbit's eyes after topically and subconjunctivally administrated with levofloxacin (LVFX).Methods:
The concentrations of LVFX in the cornea,aqueous humor,iris-ciliary body,lens and vitreous at different times were measured by high performance liquid chromatography after 0.3% LVFX were topically and subconjunctivally administrated into rabbits.Results:
The penetration of LVFX into the cornea,iris-ciliary body,lens and vitreous after subconjunctival injection was significantly higher than that of topically applied one( P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chongqing Medical University
Year:
2003
Type:
Article
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