The effects of serotomin on ionic channels currents and membrane potentials of the guinea pig proximate colon myocytes / 中华消化杂志
Chinese Journal of Digestion
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-572814
ABSTRACT
Objective To investigate the effects of serotonin(5-HT) on the ionic channels currents and membrane potentials of single guinea pig proximate colon myocytes. Methods Cell images before and after contraction were captured and analyzed with an imag e analysis software. Channels currents, action potential (AP) and resting potent ial (RP) were recorded with an EPC-9 amplifier. Results The direct actions of 10 ?mol/L 5-HT to myocytes resulted in followin g effects Firstly, the exogenous stimulated peak values of AP reduced to 60%?7 .3%(n=7,P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Digestion
Year:
2001
Type:
Article
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