The correlation of HBV-DNA with liver enzyme indicators and other markers of hepatitis B virus in chronic aclive hepatitis B patients

ABSTRACT

Research on 31 patients (include 24 man and 7 woman) at 20 to 60 years old who treated active hepatitis B at The army centre hospital 105 from 1/1999 to 6/2002. Result: HBV-DNA level in plasma increase follow agreeable rate with SGPT content SGPT increase to > 100U/L correlative HBV-DNA patients(+) ≥10copies, 16,13% HBV-DNA patients (-) from 5 to 10 copies. The development of the disease in active hepatitis B patients was showed at relationship of marks of HBV with HBV -DNA(+) 70,96%, Anti-HBV-IgG (+) 100%, anti-HBc0IIgG (+) and anti-HBc-IgM (+) 12,90%, HBV-DNA (+) and HBeAg (+) 41,94%, HBV-DNA(+) and anti-HBe (-) 38,72%. HBV-DNA may be importance mark in following up development of the disease