Relationship between endothelin-1 and nitron oxygen changes in cerebral spinal fluid and cerebral vasospasm following subarachnoid hemorrhage / 介入放射学杂志
Journal of Interventional Radiology
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-573004
ABSTRACT
Objective To investigate the relationship between endothelin-1(ET-1)and NO in cerebral spinal fluid(CSF) and cerebral vasospasm(CVS) following experimental subarachnoid hemorrhage(SAH).Methods An experimental CVS model was achieved by twice injections of fresh autologous arterial blood into the cisterna magna of each animal. The contents of ET-1 and NO in CSF were measured by radioimmunological analysis and activated cadmium reduction method respectively.The degrees of CVS were analyzed through cerebral angiography(%reduction of basilar artery diamiter,%RBAD). Results The contents of ET-1 in CSF increased significantly than that before injection after SAH(P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Interventional Radiology
Year:
2003
Type:
Article
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