Study of augmenter of liver regeneration in rat testis / 重庆医科大学学报

ABSTRACT

Objective:To confirm the expression and localization of augmenter of liver regeneration(ALR) in baby,mature and the old rat testis and to evaluate the function of ALR in reproduction.Methods:ALR expression and localization in baby,mature and the old rat testis were examined by immunohistochemistry,ALR expressions of the mature rat testis and liver were examined in 12h,24h and 48h after 70 percent partial hepatectomy(PH) as well.Results:ALR was expressed in the cytoplasm and membrane of cells and it commonly existed in Leydig cells,Sertoli cells and sperm cells of rat testis,especially in spermatogonia and spermatocytes.ALR expressions differed among baby,mature and the old rat testis,in the way from the strongest to the weakest.After 70 percent PH ALR expression increased in liver,peaking in 24h,while that in testis didn't change.Conclusion:ALR expression in testis is strong which is necessary for testis development,spermatogenesis and mature sperm.The function of ALR is organ special.