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The study of genome DNA methylation in systemic lupus erythematosus / 中华风湿病学杂志
Chinese Journal of Rheumatology ; (12)2001.
Article in Chinese | WPRIM | ID: wpr-573288
ABSTRACT
Objective To study the genome DNA methylation in SLE and the related factors of DNA methylation. Methods Twenty-six cases with SLE and 20 controls were recruited to participate the study. Plasma Hcy, SAM, SAH and the MTHFR gene C677T polymorphism were measured in all patients and controls. Results {1} The SAM levels were lower significantly in SLE groups than in controls. The SAH levels were higher significantly in SLE groups than in controls. {2} There was significant inverse correlation between plasma Hcy level and SAM level (r=-0.897, P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Rheumatology Year: 2001 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Rheumatology Year: 2001 Type: Article