Drug resistance and genotyping of Enterobacter cloacae in lower respiratory tract infection / 重庆医科大学学报

ABSTRACT

Objective:To study the type of drug resistance spectrum and molecular biological characteristics of Enterobacter cloacae which infects lower respiratory tract in hospital.Methods:Drug resistance in 28 strains EC and optimal reaction system of RAPD were used to study their molecular epidemiology.Results:28 strains EC were divided into 10 types by genotype,18 types by resistance.Conclusion:Genotyping demonstrates the outbreak of multidrug resistant strains EC in ICU.This method is accurate,reliable and highly specific.It can not only provide genetic information for controlling,preventing hospital infection and tracing the infection source and the way of dissemination but also direct the clinical doctors to select sensitive antibiotics.