Effect of solanine on DNA and RNA in tumor cell of tumor-bearing mice / 中草药
Chinese Traditional and Herbal Drugs
;
(24)1994.
Article
in Chinese
| WPRIM
| ID: wpr-573902
ABSTRACT
Objective To observe the effects of solanine on DNA and RNA level in tumor cell of S_(180) and H_(22) tumor-bearing mice.Methods S_(180) and H_(22) mice were divided into solanine(37.50、18.75,and(9.37) mg/kg) groups,negative control group and cytoxan(30 mg/kg) group,whom were given drugs by sc.Levels of RNA and DNA in tumor cell membrane in every groups were examined,respectively by laser scanning confocal microtechnic technology.Results Solanine(37.50、18.75 mg/kg) groups reduced the ratio of RNA and DNA in tumor cell of both S_(180) and H_(22) mice.Conclusion Solanine can reduce the ratio of RNA and DNA in tumor cell of S_(180) and H_(22) mice,which may be one of the mechanisms of solanine's(antitumor) effect.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
1994
Type:
Article
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