Effect of phosphorus deficiency on erythrocytic morphology and function in cows
Journal of Veterinary Science
;
: 333-340, 2017.
Article
in English
| WPRIM
| ID: wpr-57414
ABSTRACT
The aim of this study was to evaluate the influence of phosphorus (P) deficiency on the morphological and functional characteristics of erythrocytes in cows. Forty Holstein-Friesian dairy cows in mid-lactation were randomly divided into two groups of 20 each and were fed either a low-P diet (0.03% P/kg dry matter [DM]) or a control diet (0.36% P/kg DM). Red blood cell (RBC) indices results showed RBC and mean corpuscular hemoglobin decreased while mean corpuscular volume increased significantly (p < 0.05) in P-deficient cows. Erythrocyte morphology showed erythrocyte destruction in P-deficient cows. Erythrocytes' functional characteristics results showed total bilirubin and indirect bilirubin concentrations and aspartate transaminase and alanine transaminase activity levels in the serum of P-deficient cows were significantly higher than those in control diet-fed cows. Activities of superoxide dismutase and glutathione peroxidase in erythrocytes were lower, while the malondialdehyde content was greater, in P-deficient cows than in control diet-fed cows. Na⁺/K⁺-ATPase and Mg²⁺-ATPase activities were lower in P-deficient cows than in control diet-fed cows; however, Ca²⁺-ATPase activity was not significantly different. The phospholipid composition of the erythrocyte membrane changed and membrane fluidity rigidified in P-deficient cows. The results indicate that P deficiency might impair erythrocyte integrity and functional characteristics in cows.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phosphorus
/
Aspartate Aminotransferases
/
Superoxide Dismutase
/
Bilirubin
/
Diet
/
Alanine Transaminase
/
Erythrocyte Indices
/
Erythrocyte Membrane
/
Erythrocytes
/
Glutathione Peroxidase
Language:
English
Journal:
Journal of Veterinary Science
Year:
2017
Type:
Article
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