Protective Effects of Extract of Xihuangcao Tea on Chemical Hepatic Injury Model / 中药新药与临床药理

ABSTRACT

Objective To investigate the protective effects of extract of Xihuangcao Tea on chemical hepatic injury in mice and rats.Methods Mouse models of chemical hepatic injury were induced by CCl4 and rat models of jaundice by ?-naphthylisothiocyanate(ANIT).Then extract of Xihuangcao Tea was administered and enzyme activity of SGPT in the serum was measured in the mice.The serum level of total billirubin was determined in the rat jaundice models.Results Compared with the models,the enzyme activity of SGPT was significantly reduced and serum total bilirubin level decreased in extract of Xihuangcao tea groups(P