Study on the Standardization of Similarity Evaluation Method of Chromatographic Fingerprints (PartⅠ ) / 中药新药与临床药理
Traditional Chinese Drug Research & Clinical Pharmacology
;
(6)1993.
Article
in Chinese
| WPRIM
| ID: wpr-574633
ABSTRACT
Objective To study the standardization of similarity evaluation method of chromatographic fingerprints. Methods Computer simulation and HPLC method were used to investigate the characteristics of different similarity evaluation methods and the criteria of characteristic variables selection in chromatographic fingerprints. Results Cosine ratio and correlation coefficient should be the first choice for similarity calculation based on chromatographic peak area. Peak area is recommend to be used as the characteristic variable for chromatographic fingerprints. Conclusion The features of the commonly used chromatographic fingerprint evaluation methods are described and their range of application are defined.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Traditional Chinese Drug Research & Clinical Pharmacology
Year:
1993
Type:
Article
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