A randomized and double-blind trial for candesartan cilexetil in treatment of essential hypertension / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)1987.
Article
in Chinese
| WPRIM
| ID: wpr-574828
ABSTRACT
Objective:
To evaluate the efficacy and safety of domestically made candesartan cilexetil in the treatment of mild to moderate hypertension.Methods:
In randomized,double-blind and parallel control trai1,58 patients with mild and moderate essential hypertension randomly received either candesartan cilexetil at 8mg daily(=29) or irbesartan at 150mg daily(=29) for 2 weeks.The patients with poor prognosis in 2weeks(DBP≥90mmHg) received extra 1 tablet daily.Results:
Significant differences in the overall response rate of candesartan or irbesartan monotherapy(75.86% VS.37.93%) was found at 2 weeks after treatment.No significant difference in the overall response rate of candesartan or irbesartan monotherapy(89.66% VS.79.33%) was found at 4 weeks after treatment.Significant differences in decreasing the range of systolic pressure in candesartan group or irbesartan group(27.52?11.90mm Hg VS.20.72?9.27 mm Hg) at sitting position and(24.59?11.87 mm Hg VS.15.90?16.22 mm Hg) at standing position were found in at 4 weeks(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
Journal of Chongqing Medical University
Year:
1987
Type:
Article
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