Study on Serum Pharmacochemistry of Shuangshenningxin Fang and its Protective Effects on Cultured Cardiomyocytes Injured by Hypoixa and Reoxygenation / 中国中医药信息杂志
Article
in Zh
| WPRIM
| ID: wpr-575232
Responsible library:
WPRO
ABSTRACT
s:Objective To study the effective ingredients of Shuangshenningxin Fang (SSNX). Methods Based on analyzing the HPLC fingerprints of rat samples obtained after orally taking SSNX, the ingredients absorbed into blood were identified. The cultured cells were subject to hypoxia and reoxygenation. The leakage of lactic dehydrogenase (LDH) from cardiomyocytes was measured. Results Fifteen ingredients were detected after oral administration of SSNX. Dl-tetarhydropalmatine (Dl-THP), salvianolic acid B (Sal B), ginsenosides (Rg1) and dehydeocorydaline (DHC) were identified. Rg1 and DHC reduced the LDH leakage (P
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Information on Traditional Chinese Medicine
Year:
2006
Type:
Article