Involvement of matrix metalloproteinase-2, -9, and tissue inhibitors of metalloproteinase-1,2 in occurrence of the accrete placenta / 中华妇产科杂志
Chinese Journal of Obstetrics and Gynecology
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-575292
ABSTRACT
Objective To investigate the roles of matrix metalloproteinase-9, -2 (MMP-9, 2), and tissue inhibitors of metalloproteinase-1,2 (TIMP-1, 2) in pathogenesis of the accretio placenta. Methods The women with the placenta accrete were recruited and the placenta (23) and deciduas tissues (9) after labor were obtained, and the placenta (28) and deciduas (11) from women without the placenta accreta were obtained as control to get, too. The expressions of MMP-9, -2, TIMP-1, 2 in the placental and decidual tissues were analyzed by real-time PCR. Results mRNA expression of MMP-9 in the placenta accreta was (3.21?0.76) copies/?g total RNA, significantly higher (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Obstetrics and Gynecology
Year:
2001
Type:
Article
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