The Association between Urine Albumin to Creatinine Ratio and Osteoporosis in Postmenopausal Women with Type 2 Diabetes
Journal of Bone Metabolism
;
: 1-7, 2016.
Article
in English
| WPRIM
| ID: wpr-57552
ABSTRACT
BACKGROUND:
Osteoporosis is a progressive bone disease that is characterized by a decrease in bone mass density and destruction of microstructure, which can lead to an increased risk of fracture. Although many studies have been published about the relationship between end-stage renal disease and osteoporosis, research on the relationship between proteinuria and the prevalence of osteoporosis is still lacking.METHODS:
We assessed 91 postmenopausal women with type 2 diabetes who visited our hospital from January 2009 to January 2012.RESULTS:
Among 91 patients, the prevalence of osteoporosis and osteopenia was 35.2% (32 cases) and 32.9% (30 cases) according to bone mineral density. The patients with microalbuminuria and macroalbuminuria (urine albumin-to-creatinine ratio [UACR] > or = 30) had a significantly higher incidence of osteoporosis compared to subjects with normoalbuminuria (P<0.05).CONCLUSIONS:
This study indicates that UACR may be a useful biomarker for increased risk of osteoporosis in postmenopausal women with type 2 diabetes who have been linked to higher UACR levels.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoporosis
/
Proteinuria
/
Bone Diseases
/
Bone Diseases, Metabolic
/
Bone Density
/
Incidence
/
Prevalence
/
Creatinine
/
Albumins
/
Kidney Failure, Chronic
Type of study:
Incidence study
/
Prevalence study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Bone Metabolism
Year:
2016
Type:
Article
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