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The Association between Urine Albumin to Creatinine Ratio and Osteoporosis in Postmenopausal Women with Type 2 Diabetes
Journal of Bone Metabolism ; : 1-7, 2016.
Article in English | WPRIM | ID: wpr-57552
ABSTRACT

BACKGROUND:

Osteoporosis is a progressive bone disease that is characterized by a decrease in bone mass density and destruction of microstructure, which can lead to an increased risk of fracture. Although many studies have been published about the relationship between end-stage renal disease and osteoporosis, research on the relationship between proteinuria and the prevalence of osteoporosis is still lacking.

METHODS:

We assessed 91 postmenopausal women with type 2 diabetes who visited our hospital from January 2009 to January 2012.

RESULTS:

Among 91 patients, the prevalence of osteoporosis and osteopenia was 35.2% (32 cases) and 32.9% (30 cases) according to bone mineral density. The patients with microalbuminuria and macroalbuminuria (urine albumin-to-creatinine ratio [UACR] > or = 30) had a significantly higher incidence of osteoporosis compared to subjects with normoalbuminuria (P<0.05).

CONCLUSIONS:

This study indicates that UACR may be a useful biomarker for increased risk of osteoporosis in postmenopausal women with type 2 diabetes who have been linked to higher UACR levels.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoporosis / Proteinuria / Bone Diseases / Bone Diseases, Metabolic / Bone Density / Incidence / Prevalence / Creatinine / Albumins / Kidney Failure, Chronic Type of study: Incidence study / Prevalence study / Prognostic study Limits: Female / Humans Language: English Journal: Journal of Bone Metabolism Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoporosis / Proteinuria / Bone Diseases / Bone Diseases, Metabolic / Bone Density / Incidence / Prevalence / Creatinine / Albumins / Kidney Failure, Chronic Type of study: Incidence study / Prevalence study / Prognostic study Limits: Female / Humans Language: English Journal: Journal of Bone Metabolism Year: 2016 Type: Article