Absorption and purification of glycyrrhizic acid with macro resin / 中成药

ABSTRACT

AIM: An optimal method for purifying glycyrrhizic acid with D-101 macro resin was developed. METHODS: The contents of glycyrrhizic acid were used as the evaluating criteria, by means of vanlillin-sulfuric acid colorimetry. RESULTS: The optimum technical operations were as follows: 10% ethanol(4 times the volume of the resin) was used to elute glycyrrhizic acid; both the current velocity of absoring and eluting were 2 mLmin, pH of the sample was 5.8 , concentration of the sample was 9 mgmL (weight of the raw materialvolume). CONCLUSION: The results show that D-101 macro resin is suitable for absorbing and purifying glycyrrhizic acid.