Determination the content of ferulic acid in compound Yangjiao soft capsules with HPLC / 重庆医科大学学报

ABSTRACT

Objective:To establish a method for determining the concent of ferulic acid in compound Yangjiao soft capsules with HPLC.Method:To determine with HPLC using C18 column(250mm?4.6mm,5?m),methanol-1% acetic acid solution(3763) as mobile phase.The flow rate was 1.0 ml/min and the detecting wavelength was 320nm.Results: Ferulic acid had good linear relation within the range from 6 to 60?g/min,r =0.9995.The average recovery rate was 100.3%,RSD=1.68%(n=9).Conclusion:The method is with good resolution,accurate and reproducible,which can be used for determining the content of ferulic acid in compound Yangjiao soft capsules.