Expression of VEGF-C in human breast cancer and its implication / 重庆医科大学学报

ABSTRACT

Objective:To investigate the relationship between the expression of vascular endothelial growth factor-C(VEGF-C) proteins and biological behavior of breast cancer.Methods:Immunohistochemical staining was used to detect the expression of VEGF-C proteins in 12 cases of mammary fibroma,35 cases of mammary cystic hyperplasia,45 cases of breast cancer.Results:VEGF-C protein was absent in mammary fibroma,the expression rate of VEGF-C protein in mammary cystic hyperplasia was 20.0%(7/35),The expression rate of VEGF-C in breast cancer was 71.1%(32/45),and it was significantly different compared with mammary cystic hyperplasia(P