Correlation Between in vitro Chemosensitivity of Antineoplastic Drugs and its Clinical Response and Prognosis in Human Colorectal Cancers / 药物流行病学杂志
Chinese Journal of Pharmacoepidemiology
;
(4)2006.
Article
in Chinese
| WPRIM
| ID: wpr-576351
ABSTRACT
Objective:
To study the correlation between in vitro chemosensitivity of Fluorouraci(5-Fu) + Mitomycia (MMC) and its clinical response and prognosis in human colorectal cancers.Method:
The chemosensitivity of 5-Fu + MMC was tested in 169 Dukes B and C colorectal cancers with the MTT method,and the progression-free internal and prognosis in 4 years following the surgery were observed.Result:
Based on the in vitro chemosensitivity of 5-Fu + MMC, 100 patients were divided into an antagonistic group(28 patients) in which their relapse rates were 57. 1% and a synergistic-additive group(72 patients) in which their relapse rates were 22.2% (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Pharmacoepidemiology
Year:
2006
Type:
Article
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