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Influence of Different Extraction Technology on Pharmacodynamic Action of Drug Pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba / 中药新药与临床药理
Traditional Chinese Drug Research & Clinical Pharmacology ; (6)1993.
Article in Chinese | WPRIM | ID: wpr-576741
ABSTRACT
Objective To compare the influence of different extraction technology on the pharmacodynamic actions of drug pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba.Methods The influences of water extraction,alcohol extraction,and SFE-CO2 extraction on pharmacodynamic actions of drug pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba were evaluated by mice intestine propulsive motility test,rats repelling acute gastric mucosa damage test,mice twisting test and hot-plate test.Results The paired drugs extracted by SFE-CO2 combining with water extraction or alcohol extraction had better pharmacological actions.Conclusion This study provides a scientific basis for optimizing the extraction technology of drug pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Traditional Chinese Drug Research & Clinical Pharmacology Year: 1993 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Traditional Chinese Drug Research & Clinical Pharmacology Year: 1993 Type: Article