Pharmacodynamics of Yajiao Hadun San Ⅰ / 中成药

ABSTRACT

AIM: To study the pharmacodynamics of Yajiao Hadun San(Vitex trifolia;streptocaulon griffibhii;Asparagus pseudofilicinus;Inula cappa;Benincasa hispida;Tacca esquirolli). METHODS: The pyrexia model rat induced with active yeast,the mice's auricular swelling test caused by croton oil;the mice's toe swelling test caused by albumen;the mice's twisting body test caused by the irritation of acetic acid and the mice's carbon clearance test were used to determine antipyretic,analgesic,anti-inflammation effect and immunity function of Yajiao Hadun San. RESULTS: Yajiao Hadun San could reduce the anus temperature of the pyrexia model rat,inhibit the mice's toe and auricular swelling,reduce the times of twisting body sharply and also increase the rate of eliminating colloid carbon in mice. CONCLUSION: Yajiao Hadun San has certain antipyretic,anti-inflammation,analgesic effect and enhance the phagocytosis of mono-karyon macrophage in mice.