Quality standard for Xianglian Zhixie Capsule / 中成药

ABSTRACT

AIM:To establish the quality standard for Xianglian Zhixie Capsule(Radix Aucklandiae,Rhizoma Coptidis).METHODS:Radix Aucklandiae,Rhizoma Coptidis of Xianglian Zhixie Capsule were identified by TLC.Dehydro-costunolide,costunolide were determined by HPLC together.RESULTS:The characteristic identification by TLC was distinct and highly specific.The quantitative evaluation of dehydro-costunolide had the linear range of 0.217 4-2.174 ?g(r=0.999 9,n=6),the average recovery was 96.25%(RSD=1.37%,n=6).The quantitative evaluation of costunolide had the linear range of 0.199 2-1.992 ?g(r=0.999 3,n=6),the average recovery was 101.77%(RSD=1.23%,n=6).CONCLUSION:The method is reliable,accurate and specific.It can be used for quality control of Xianglian Zhixie Capsule.