Quality standard for Guanxin Plaster / 中成药

ABSTRACT

AIM:To establish the quality standard for Guanxin Plaster(Radix et Rhizoma Salviae miltiorrhizae,Rhizoma Chuanxiong,Olibanum,etc). METHODS: Radix et Rhizoma Salviae miltiorrhizae;Rhizoma Chuanxiong and Radix Angeliae pubescentis of Guanxin Plaster were identified by TLC.Camphor,menthol and borneolum syntheticum were cletermined by GC together. RESULTS: The characteristic identification by TLC was distinct and highly specific.Camphor showed a good liner relationship at a range of 0.095 ?g-0.95 ?g,(r=0.999 7,n=5).Menthol showed a good linear relationship at a range of 0.123 ?g-1.23 ?g,r=0.999 6,n=5).Borneolum syntheticum showed a good liner relationship at a range of 0.202 ?g-2.02 ?g,(r=0.999 7,n=5).The average recoveries were 99.6%(RSD=1.9%) for camphor,98.4%(RSD=2.0%) for menthol,98.2%(RSD=3.8%) for bomeolum syntheticum. CONCLUSION: The method is reliable,accurate and specific.It can be used for quality control of Guanxin Plaster.