Study on Extraction Process of Danlong Kangchi Capsules / 中国中医药信息杂志

ABSTRACT

Objective To control the quality of Danlong Kangchi Capsules, fully extract efficiency ingredients and ensure the therapeutic effect by studying the extraction process of the capsule. Methods With the extracting quantity of tanshinoneⅡA, ginsenoside Rb1 and Rg1, Icariin and extract ratio as indexes, the better process parameters with ethanol or water extracting were selected by simple factor test and orthogonal test to Danlong Kangchi Capsules. Results The herbs such as root of red-rooted salvia were extracted by 75% ethanol as a solvent, reflux extracting two times, adding 8 times and 6 times solvent volume respectively, extracting 1.5 and 1.0 hour respectively. Dregs after ethanol extracting and the herbs such as herba Epimedii were decocted by waters soaking 0.5 hour, extracting two times, adding 12 times and 10 times solvent volume respectively, extracting 2.0 and 1.5 hours respectively. Conclusions Extracting processes were validated to be stable and feasible.