Regulation Effect of Shengmai Injection on T Helper Cells Balance in Patients with Graves Disease / 中国中医药信息杂志

ABSTRACT

Objective To explore the changes of Th1/Th2 cytokine in patients with Graves disease(GD) and the regulation effect of Shengmai Injection on its balance.Methods The patients with GD were randomly divided into 2 groups,the Shengmai treated group and the Methimazole treated group,30 cases per group and 30 healthy subjects were enrolled in this study.The serum concentrations of their Th1 cytokine(IFN-?) and Th2 cytokine(IL-10) were assayed by ELISA before and after treatment.Results The serum levels of INF-? and IL-10 in patients with GD were significant higher and the ratio of INF-?/IL-10 were significant lower than healthy subjects(P