Expression and activity detection of IL3-PE38KDEL / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-578897
ABSTRACT
Objective:
To prepare a new type of anti-leukemia immunotoxin with killing activity.Methods:
The method of cytotoxicity was used to study the activity of the immunotoxin after the induction of IPTG.Results:
The expressed fusion proteins were detected mostly as inclusion bodies at high level.The result showed IL3-PE38KDEL had liable activity of toxicity.Conclusion:
The fusion protein IL3-PE38KDEL has good biological activity,which paves way for the further study on its treatment of leukemia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Journal of Chongqing Medical University
Year:
2007
Type:
Article
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