CT and MRI manifestations of neurofibromatosis in cranium and spinal column / 重庆医科大学学报

ABSTRACT

Objective:To analyze CT and MRI manifestations of cranium and spinal column with neurofibromatosis type1 and 2 to improve the diagnostic accuracy.Methods:CT and MRI images of 16 cases of neurofibromatosis confirmed by clinics and pathology were analyzed retrospectively.2 cases were examined by CT and 14 cases by MRI.There were 6 cases of NF1 and 10 cases of NF2.The abnormal CT and MRI manifestations of the lesions were analyzed.Results:NF1 manifestations were as follows5 cases of multiple schwannomas were displayed on MRI with intraspinal and paraspinal lesions,and along with 1 case of syringomyelia,2 cases of right great psoas muscle schwannomas.1 case had defect of right great wing of the sphenoid on CT.NF2 manifestations were as follows5 cases had bilateral acoustic neuromas and multiple meningioms,and with 2 cases of multiple neurofibromas in the occipital,cervical and lumbar soft tissues;2 cases of bilateral internal auditory canal enlarged on CT;1 case of choroid plexus in the lateral ventricle abnormal calcification,1case of right troehlear nerve schwannoma.5 cases had single acoustic neuromas,with 3 cases of schwannomas in spinal canal,and 1case of intramedullary cervical spinal cord ependymoma and syringomyelia;3 cases of multiple meningioms and with 1 case of schwannoma on the facial nerve,vestibular and trigemina nerve;and 3 cases had abnormal signal lesions in the brain parenchyma.Conclusion:Neurofibromatosis type 1 and 2 had characteristic CT and MRI manifestations in cranium and spinal column,which could be diagnosed correctly in clinic.