Pharmacodynamic Research of Tongmai Oral Liquid on Preventing and CuringⅡPeriod Diabetic Nephropathy / 中国中医药信息杂志
Chinese Journal of Information on Traditional Chinese Medicine
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-579315
ABSTRACT
Objective To investigate the effect of Tongmai oral liquid on the early diabetic nephropathy. Methods Diabetic nephropathy rats were induced by excision of the right kidney and a single intraperitoneal injection of streptozotocin (STZ). Forty male Wistar rats were divided randomly into 3 groupsTongmai group, nephrotic model group, and normal group. At the end of the 8th week, the rats general states and some parameters such as kidney hypertrophy index, 24 h urine volume, blood glucose, 24 h urinary microalbumin (24 h UMA), renal function [serum creatinine (Cr), blood urea nitrogen (BUN)], serum lipid, and the change of nephritic pathologic lesion were measured. Result Compared with the model group, general states in Tongmai group were improved, there was a considerable increase on body weight (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Information on Traditional Chinese Medicine
Year:
2006
Type:
Article
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