Clinical Study on Jiangzhi Decoction in Regulating Lipometabolic Disorder with Stagnation of Phlegm and Blood-stasis / 中药新药与临床药理

ABSTRACT

Objective To investigate the therapeutic effect of Jiangzhi Decoction(JD) for the treatment of disordered lipid metabolism.Methods With Zhibituo Capsule as the control capsule,a random,paralleled and positive controlled clinical trial was carried out.A total of 64 patients were equally randomized into the treatment group and control group,and the treatment lasted 4 weeks.Results After administration,the level of total cholesterol(TC),triglyceride(TG),and arteriosclerosis index(AI) were reduced,the high density lipoprotein cholesterol(HDL-C) level was increased,and the sum of the decrease of electrocardiogram(ECG) ST segment was markedly improved in the treatment group,the difference being significant compared with those before treatment.In the treatment group,oppressive pain in the chest and hypochondrium,dizziness,limb numbness,poor appetite and headache were much relieved,and the relief of oppressive pain in the chest and hypochondrium,dizziness,and poor appetite was obvious as compared with the control group.Conclusion JD has good curative effect on disordered lipid metabolism with stagnation of phlegm and blood-stasis,in particular on relieving the clinical symptoms.