Expres s ion of SDF-1-CXCR4-VEGF-C and the relationship with lymph node metastasis in laryngeal carcinoma / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-579637
ABSTRACT
Objective:
To investigate the relationship of CXCR4,VEGF-C and SDF-1 in human laryngeal carcinoma and discuss the significance of the three indexs in lymph node metastasis.Methods:
The expression of CXCR4,VEGF-C and SDF-1 was detected by reverse transcription polymerase chain reaction(RT-PCR)and immuno-histochemical SP in 10 cases of adjacent normal tissue,45 cases of laryngeal carcinoma tissue and cervical lymph node tissue.Results:
Not in the mRNA but the level of proteins,The positive rate of the expression of CXCR4 and VEGF-C were 78%,67%and 78%,71%in primary tumor cells,were altogether higher than that in adjacent normal tissue(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chongqing Medical University
Year:
2003
Type:
Article
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