Analysis of Literature about Ceftriaxone-induced Anaphylactic Shock in 70 Cases / 药物流行病学杂志

ABSTRACT

Objective:To study the characteristics,related factors and precautionary measures of ceftriaxone-induced anaphylactic shock,and provide reference for clinical safe medication.Method:The literature between January, 1994 and December,2007 was collected from Chinese Journal Full-text Database,Chinese Science and Technology Journal Full-text Database,and Wanfang Medicine Data China info,70 cases with ceftriaxone-induced anaphylactic shock were reviewed and analyzed.Result:Of the 70 cases,43(61.4%) were male,and 27(38.6%) were female.64(91.4%) received intravenous fusion or intravenous injection and 6(8.6%),intramuscular or prostate capsule injection.Most of the anaphylactic shock cases occurred within 20 minutes(71.2%) after administration.61 cases recovered(87.1%) and 8 cases died(11.4%) and 1 cases became vegetable(1.5%) after treatment.Conclusion:The ceftriaxone-induced anaphylactic shock is rapid so as to be timely rescued.Patients should be asked about their case history and medication history in detail before treatment in order to reduce occurrences of shock.