Systematic review on effect of shuxuetong injection on diabetic peripheral neuropathy / 重庆医科大学学报

ABSTRACT

Objective:To evaluate the therapeutic effect of shuxuetong injection on diabetic peripheral neuropathy (DNP). Methods: Odds ratio of symptom improving between the treatment and control group was analyzed. Related published literatures on effect of shuxuetong on DPN were fully searched and screened through computed database. The data were extracted for summarizing all the studies,calculating the pooled OR and its 95% confidence interval(95% CI),and testing the overall effects by RevMan 4.3.1. Both publication bias analysis and sensitivity analysis were performed for evaluating the reliability and stability of the meta-analysis. Other indexes in the literatures which were not adapted for meta-analysis were also described.Results:Eleven literatures,totally 937 cases,were obtained. Some heterogeneity were discovered between the studies (P=0.09). Shuxuetong injection may significantly relieve the symptom of patients with diabetic peripheral neuropathy. Its OR and 95%CI was 6.05 (3.83,9.55)(P