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Influence of Qi-strengthening,Blood-activating and Toxin-removing Therapy on Plasma and Colonic P-selectin in Ulcerative Colitis Rats / 广州中医药大学学报
Journal of Guangzhou University of Traditional Chinese Medicine ; (6)2004.
Article in Chinese | WPRIM | ID: wpr-580090
ABSTRACT
Objective To investigate influence of Qi-strengthening,blood-activating and toxin-removing therapy on plasma and colonic P-selectin in ulcerative colitis(UC) rats.Methods Trinitrobenzene sulfonic acid(TNBS) was used for the establishment of SD rat models of UC.UC rats were randomized into the model group,western medicine group(gastric gavage of suspension of Olsalazine Sodium Capsules 0.266 g?kg-1?d-1),and herbal medicine group(gastric gavage of Kuijie Fufa Recipe 20 g?kg-1?d-1).Meanwhile,a normal control group was set up.After medication for 10 and 30 days,and after drug withdrawal for 10 days,plasma P-selectin level was detected by enzyme-linked immunosorbent assay,and colonic P-selectin expression was detected by immunohistochemical assay.Results Plasma P-selectin level was increased in the model group in different time(P

Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Journal of Guangzhou University of Traditional Chinese Medicine Year: 2004 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Journal of Guangzhou University of Traditional Chinese Medicine Year: 2004 Type: Article