Therapeutic Effect of External Application and Oral Use of Herba Seu Radix Violae Japonicae for the Treatment of Chronic Osteomyelitis / 广州中医药大学学报

ABSTRACT

Objective To observe the therapeutic effect of external application and oral use of Herba Seu Radix Violae Japonicae(HSRVJ) for the treatment of chronic osteomyelitis.Methods Sixty chronic osteomyelitis were randomized into the treatment group and the control group.The two groups received conservative routine antibiotic treatment.The treatment group received external application and oral use of HSRVJ additionally.Seven days constituted one treatment course,and the treatment lasted 6 courses.The changes of erythrocyte sedimentation(ESR) and C-reactive protein(CRP) were compared in the two groups before treatment and every 2 courses.Meanwhile,the clinical cure rate and the total effective rate were observed in the two groups.Results The cure rate was 46.67% and the total effective rate was 86.67% in the treatment group,and was 20.00% and 63.33% in the control group respectively.ESR and CRP decreased gradually every 2 courses in the two groups(P