A clinical analysis of synthetic therapy effect and prognostic factors in 107 patients with breast cancer / 重庆医科大学学报

ABSTRACT

Objective:To investigate the synthetic therapy effect and prognosticfactorsin 107 patientswith breastcancer and explore the relationship between some clinical-pathological factors and patients' prognosis.Methods:Between Jan,2000 and Dec,2003,the clinical-pathological materials of 107 breast cancer cases who have received synthetic therapy,including radiotherapy,surgery,chemotherapy and endocrine therapy,were analyzed.The correlation of age,menopausal status,tumor size,axillary lymph nodal status,TNM stage,hormone receptor status and endocrinetherapy with prognosis of breast cancer was evaluated.Results:The overall survival and disease-free survival of the whole patients were 90.3 and 74.8 months,respectively.Analysis revealed that overall survival and disease-free survival of this group were significantly associated with tumor size,axillary lymph nodal status and TNMstage(P0.05).Conclusion:Our data demonstrate that tumor size,axillary lymph nodal status and TNM stage are significant independent indicators of prognosis in breast cancer respectively,and age,menopausal status,hormone receptor status and endocrine therapy are not significant factors of prognosis.