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Effects of Mycobacterium Phlei on Funcitonal States of Th_1/Th_2 in Patients with COPD and Preventive Effects on AECOPD / 药物流行病学杂志
Chinese Journal of Pharmacoepidemiology ; (4)2007.
Article in Chinese | WPRIM | ID: wpr-580574
ABSTRACT

Objective:

To investigate the effects of Mycobacterium Phlei on functional states of Th_1/Th_2 in patients with chronic obstructive pulmonary disease(COPD),and clinical effects on the prevention of acute exacerbation of chronic obstructive pulmonary diseases(AECOPD).

Method:

60 patients with COPD of gradeⅡwere randomly divided into a treatment group and controlled group.The controlled group were given a routine therapy,while the treatment group were given utilins in addition to the routine treatment.The contents of?-interferon(IFN-?) and interleukin-4(IL-4) in their peripheral blood and their clinical efficacy were observed before and after the treatment.

Result:

Before and after the treatment, IFN-?/IL-4 ratio in the treatment group was 1.39?0.20 and 1.94?0.31 respectively(P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pharmacoepidemiology Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pharmacoepidemiology Year: 2007 Type: Article