Analysis of Utilization and Adverse Drug Reaction of Aminoglycoside Antibiotics in Our Hospital During 2005-2008 / 药物流行病学杂志
Chinese Journal of Pharmacoepidemiology
;
(4)2007.
Article
in Chinese
| WPRIM
| ID: wpr-580905
ABSTRACT
Objective:
To investigate the use and adverse drug reaction of aminoglycoside antibiotics(AmAn) in our hospital during 2005-2008,and to valuate its rationality for reducing its adverse drug reaction.Methods:
The data about AmAn's consumption quantity and consumption sum in our hospital were analyzed with the DDD method.Results:
Etimicin dominated the first place among AmAn in our hospital,and replaced Gentamicin.The quantities of Netilmicin,Isepamicin and amikacin were stable.In the same period,the main adverse drug reactions were allergic-like reactions,skin rash,ototoxicity and local numbness.Conclusion:
Careful selection according to etiology,genetics testing,stronger monitoring of blood concentration and rational dosage treatment will provide a good prospect in the use of AmAn for the multifaceted gram-negative bacteria infection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pharmacoepidemiology
Year:
2007
Type:
Article
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